19. October 2020 15:52
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Piperacillin 4mg Tazobactam 500mg called also Piperacillin Tazobactam 4.5 injection available in pcd pharma franchise with brand name PERTH 4.5 and also
provide in third party manufacturing.
PERTH 4.5
Composition : Piperacillin 4mg, Tazobactam 500mg
Piperacillin :Piperacillin is a broad spectrum β-lactam antibiotic of the ureidopenicillins class.
Tazobactam: Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases.
Mode Of Action :-
Piperacillin: Tazobactam is given with Piperacillin to enhance the activity of Piperacillin in eradicating bacterial infections. Piperacillin kills bacteria by inhibiting the synthesis of bacterial cell walls. It binds preferentially to specific penicillin –binding protein (PBPs)located inside bacterial cell walls.
Tazobactam: Tazobactam is as a β-lactamases inhibitor. It is a penicillanic acid sulfone derivative and β-lactamases inhibitor with antibacterial activity. It contain β-lactam ring and irreversibly binds to β-lactamases at or near its active site.
Indications and usage:-
Piperacillin:
- It is used to treat urinary tract infections
- Bone and joint infections
- Severe vaginal infections
- Stomach infections
- Skin infections
- Pneumonia
Tazobactam:
- It is used to treat urinary tract infections
- Bone and joint infections
- Severe vaginal infections
- Stomach infections
- Skin infections
- Pneumonia
Side effects:-
Piperacillin: Common side effect:
- Vomiting
- Diarrhea
- Constipation
- Rash/itching
- Pain at site of injection
- Runny nose
- Agitation
- Stomach pain
- Insomnia
Tazobactam: Common side effect:
- Vomiting
- Diarrhea
- Constipation
- Rash/itching
- Pain at site of injection
- Runny nose
- Agitation
- Stomach pain
- Insomnia