Impileo Lifescience pvt ltd

BEST PCD PHARMA FRANCHISE OF Calcium carbonate eq. to elemental calcium, Magnesium Hydroxide eq. to elemental magnesium zinc sulphate monohydrate eq. to elemental zinc & vitamin d3

 

CRUM-CZ

Composition :- Calcium carbonate eq. to elemental calcium, Magnesium Hydroxide eq. to elemental magnesium zinc sulphate monohydrate eq. to elemental zinc & vitamin d3

Calcium carbonate: It is dietary supplement used when the amount of calcium taken in the diet is not enough .Calcium carbonate also is used as an antacid to relieve heartburn ,acid indigestion and upset stomach.

Calcitriol: Calcitriol is the active form of vitamin D , normally made in the kidney.A manufactured form is used to treat kidney disease with low  blood calcium ,  hyperparathyroidism due to kidney disease.

Zinc: It is dietary supplement which is used to treat zinc deficiency and to prevention the conditions in those at high risk.

Mode Of Action:-

Calcium carbonate:

It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions .subsequent increases in PH may inhibit the action pepsin. An increase in biocarbonte ions and prostaglandins may also confer cytoprotective effects.

Calcitriol :The active form of vitamin D binds to intracellular receptors that then function as transcriptions factors to modulase gene expression like the receptors for other steroid hormones and thyroid hormones , the vitamin D receptor has hormone binding and DNA binding domains.

Zinc: There are several mechanism of action of zinc on acute diarrhea  , some of which are specific to the gastrointestinal system. zinc restores mucosal barrier integrity and enterocyte brush border enzyme activity.it promote the production of antibodies and circulating lymphocytes against intestinal pathogen.

Indications and usage:-

Calcium carbonate:

• It is used to prevent or treat low blood calcium level in people who do not get enough calcium from their diet.
• It used in weak bones (osteomalacia)
• Decreased activity of the parathyroid gland (hypoparathyroidism)
• It may also used in pregnant women

Calcitriol:

• It helps to control parathyroid hormone and the level of certain minerals e.g. calcium phosphorus
• It is also used to treat calcium deficiency (hypocalcemia)and metabolic bone disease in people who are receiving diagnosis
• Calcitriol is also use to treat calcium deficiency in people with hypoparathyroidism caused by surgery , disease or other conditions.

Zinc:  It is effective for:

• Zinc deficiency
• Diarrhea
• Peptic ulcer
• Acne ,skin lesions
• Age related vision loss
• Anorexia
• Burns ,bed sores
• Common cold
• Depression , weak bones , pneumonia
• Complication during pregnancy

Side effects:-

Calcium carbonate :

• Loss of appetite
• Constipation
• Gas
• Calcitriol:

• Nausea and vomiting
• Weakness
• Headache
• Constipation
• Dry mouth
• Fast or slow heart rate
• Drowsiness
• Stomach pain

Zinc:

• Nausea and vomiting
• Stomach pain
• Diarrhea
• Changes in taste

Low good HDL cholesterol